Myocardial infarct delineation in vivo using diffusion tensor MRI and the tractographic propagation angle
نویسندگان
چکیده
Background Delayed gadolinium enhancement (Gd-DE) is widely used to detect scar formation following myocardial infarction (MI) [1], but cannot be performed in patients with renal impairment. Here we use the tractographic propagation angle (PA), a novel index derived from 3D diffusion tensor MRI (DTI), to detect changes in myocardial fiber architecture post-MI [2]. We compare image segmentation based on the tractographic PA to infarct delineation with GdDE.
منابع مشابه
Myocardial Scar Delineation Using Diffusion Tensor Magnetic Resonance Tractography
BACKGROUND Late gadolinium enhancement (LGE) is the current standard for myocardial scar delineation. In this study, we introduce the tractographic propagation angle (PA), a metric of myofiber curvature (degrees/unit distance) derived from diffusion tensor imaging (DTI), and compare its use to LGE and invasive scar assessment by endocardial voltage mapping. METHODS AND RESULTS DTI was perform...
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